Do the job, but spare the irritation:
A team led by Gopal Gupta at the Central Drug Research Institute in Lucknow, India, has created two new molecules that kill sperm 25 times more effectively than commonly used spermicide, Nonoxynol-9 (N9). Nonoxynol-9, an active ingredient in most spermicidal creams, is a detergent that kills almost all living cells by destroying their fatty membranes. Though this kills the sperm, it also wipes out some of the normal vaginal bacteria that help prevent bladder and yeast infections. This can also irritate the cells in the cervix and vaginal wall in some women, as well as increase their chances of contracting sexually transmitted diseases such as HIV and gonorrhea. According to Gopta, “our molecules don’t rip open the membrane to exert their action.” These new molecules are also non-toxic to cultures of human cervical cells and bacteria commonly found in the vagina.
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